Leber’s is the number one genetic cause of blindness in childhood.

Leber Congenital Amaurosis is an eye disorder that primarily affects the retina, which is the specialized tissue at the back of the eye that detects light and colour. People with the disorder typically have severe visual impairment beginning in infancy, making Leber’s the number one genetic cause of blindness in childhood. It is estimated that Leber’s affects approximately 15,000 people in the West world, and many more in the rest of the world.

Now a person with Leber’s has become the first to receive a CRISPR–Cas9 gene therapy administered directly into their body. The treatment is part of a landmark…


Nzambi Matee is a Nairobi-based entrepreneur and inventor who is the founder of a startup which recycles plastic waste into bricks that are stronger than concrete. Nzambi launched her company initiated following the development of a prototype machine that turns discarded plastic into paving stones. Each day her factory can produce 1,500 churned plastic pavers, which are prized locally not just for the quality, but for how affordable they are.

“It is absurd that we still have this problem of providing decent shelter — a basic human need. Plastic is a material that is misused and misunderstood. …


At it’s heart artificial intelligence is about efficiency and productivity. In a world of omnipresent AI that is present across every segment of economic activity, people will be able to do more with less. This leads to greater economic wealth, health and also increased leisure and family time.

For evidence of the economic and social benefits that AI will bring, look no further than the fact that workers in richer countries tend to work fewer hours than workers in poorer countries. …


The month was October 2019. As I sat in London being filmed for an interview for the Tej Kohli Foundation about the year ahead (see below), I could not have envisaged the oncoming global pandemic that would dominate 2020.

As I watch that video today, it’s hard not to conclude that many of the challenges I talked about then have not merely persisted, but have grown even larger and more pervasive in their potential to ignite global havoc.

We (rightly) talk about them less because the world is in survival mode amidst the biggest crisis since World War II. But…


Investments to scale up energy production with cheap electric power from renewable sources are not only an opportunity to reduce emissions, but also to achieve more economic growth in the poorest places in the world.

Artist Picasso famously said that “good artists copy, great artists steal”. And so it is with this same sentiment in mind that I disclose that this blog post will be drawing heavily from a study by the fantastic Our World In Data, which can be explored in full by clicking here. And with that disclaimer done, let us ask two important questions: Why did renewable energy become so cheap, so fast? And can we use this as a global opportunity for green growth?


Tej Kohli is the founder of the not-for-profit Tej Kohli Foundation whose ‘Rebuilding You’ philosophy supports the development of scientific and technological solutions to major global health challenges whilst also making interventions to rebuild people and communities around the world. Tej Kohli is also an impact investor who backs growth-stage artificial intelligence and robotics ventures through the Kohli Ventures investment vehicle.

Twitter @MrTejKohli.

Francisco Lopera, a neurologist, has been painstakingly collecting brains, birth and death records from one sprawling Colombian family to study Alzheimer’s. Credit: The New York Times

This week an annual report arrived on my desk from Massachusetts Eye And Ear Hospital in Boston. The modest 21-page report leads with the news that its ‘Bold Science. …


Tej Kohli is the founder of the not-for-profit Tej Kohli Foundation whose ‘Rebuilding You’ philosophy supports the development of scientific and technological solutions to major global health challenges whilst also making interventions to rebuild people and communities around the world. Tej Kohli is also an impact investor who backs growth-stage artificial intelligence and robotics ventures through the Kohli Ventures investment vehicle.

Twitter @MrTejKohli.

Elon Musk’s Neuralink brain implant

Because of Elon Musk, implanted bionic devices have become more prominent in the public eye. And so it feels like an apt time to consider what the future of implanted bionic devices really looks like, and more…


Tej Kohli is the founder of the not-for-profit Tej Kohli Foundation whose ‘Rebuilding You’ philosophy supports the development of scientific and technological solutions to major global health challenges whilst also making interventions to rebuild people and communities around the world. Tej Kohli is also an impact investor who backs growth-stage artificial intelligence and robotics ventures through the Kohli Ventures investment vehicle.

Twitter @MrTejKohli.

Source: http://www.tejkohlicorneainstitute.com

A recent article in The Economist profiled an ophthalmologist who has had to also become a computer scientist to tackle the challenge of a falling number of ophthalmologists at a time when demand in increasing (in the…


Tej Kohli is the founder of the not-for-profit Tej Kohli Foundation whose ‘Rebuilding You’ philosophy supports the development of scientific and technological solutions to major global health challenges whilst also making interventions to rebuild people and communities around the world. Tej Kohli is also an impact investor who backs growth-stage artificial intelligence and robotics ventures through the Kohli Ventures investment vehicle.

Twitter @MrTejKohli.

SOURCE: Our World In Data

I am a big data guy. I am fascinated to the point of obsession with how we can create new modalities of data to feed into machine learning and bring together the myriad components of artificial intelligence…


Tej Kohli is the founder of the not-for-profit Tej Kohli Foundation whose ‘Rebuilding You’ philosophy supports the development of scientific and technological solutions to major global health challenges whilst also making interventions to rebuild people and communities around the world. Tej Kohli is also an impact investor who backs growth-stage artificial intelligence and robotics ventures through the Kohli Ventures investment vehicle.

Twitter @MrTejKohli.

Gross appearance of the regenerated cornea of all 10 patients who received bioengineered corneal implants comprising recombinant human collagen. Left two columns: patients at 2 years post-operation. Right two columns: The same patients at 4 years post-surgery. Compiled figures adapted from Fagerholm et al. (2010, 2014), with permission from AAAS and Elsevier.

A watershed point in corneal transplant surgery is rapidly being approached. …

Tej Kohli

Technologist, entrepreneur & investor interested in deep tech & e-commerce. Also owner of Zibel Real Estate & founder of the not-for-profit Tej Kohli Foundation

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